Champions-elect Liverpool got their title push back on track with a narrow win over West Ham, while second-place Arsenal were held to a draw against Brentford.
At the bottom end of the table, Wolves pulled off a surprise 4-2 win against Tottenham Hotspur and Ipswich held Chelsea to a 2-2 draw.
Elsewhere, Newcastle's fine form continued with a 4-1 hammering of Manchester United.
Using Flashscore's player ratings system, we have selected an XI of the Premier League's best performers over the weekend.
GK - Kepa Arrizabalaga, 8.2 (Bournemouth)
This week's best performing goalkeeper by some distance was Bournemouth's Kepa Arrizabalaga, who made seven saves and kept a clean sheet in the Cherries' 1-0 win over Fulham.
The Spaniard has come under scrutiny throughout his career but seems to be settled on the south coast and is playing an important role in their push for European football - with his latest contribution helping secure a huge three points.
DEF - Thomas Partey, 8.5 (Arsenal)
Thomas Partey has played out of position at various points in the campaign for Arsenal and was asked to do so once again during their 1-1 draw against Brentford.
Usually a midfielder, Partey excelled in his secondary role and even got on the score-sheet for the Gunners with a powerful effort following a sweeping counterattack.
The Ghanaian also impressed defensively with four clearances and an interception.
DEF - Virgil van Dijk, 7.9 (Liverpool)
Virgil van Dijk has been a huge talking point at Liverpool over the past few months due to his ongoing contract situation, but the outside noise didn't seem to affect him during the Reds' 2-1 win over West Ham.
The defender netted the winning goal late in the second half to seal a huge three points for Liverpool - sending them within touching distance of a second Premier League title.
DEF - Rayan Ait-Nouri, 8.8 (Wolves)
Wolves defender Rayan Ait-Nouri excelled in their 4-2 win against Spurs, grabbing a goal and an assist during the match to earn an 8.8 player rating.
The Algerian has quietly had one of the better campaigns from any left-back in the division and once again proved his value with an exceptional showing.
His score was the joint-highest of any performer over the weekend alongside Brighton's Joao Pedro.
MID - Ben Johnson, 8.5 (Ipswich)
Ipswich pulled off a shock 2-2 draw against Chelsea despite their poor form throughout the season.
One of the Tractor Boys' top performers on the day was Ben Johnson, who bagged a goal and an assist from right wing-back.
The Englishman put in an excellent showing by completing five key passes, creating two big chances and making five clearances.
MID - Amadou Onana, 8.0 (Aston Villa)
Amadou Onana enjoyed a solid showing during Aston Villa's 3-0 win against the already relegated Southampton.
The midfielder dominated the game with six tackles, three interceptions and three clearances while also winning nine duels in what turned out to be a solid display from the Belgian.
MID - Julio Enciso, 8.5 (Ipswich)
Another one of Ipswich's top performers in their draw with Chelsea was Brighton loanee Julio Enciso, who - like Johnson - grabbed a goal and an assist at Stamford Bridge.
Enciso was key to the Tractor Boys' attacking play and took his goal well with an instinctive finish from close range.
MID - Harvey Barnes, 8.4 (Newcastle)
Harvey Barnes scored twice in Newcastle's 4-1 win against Manchester United.
The winger has struggled for minutes at times throughout the season, but took his chance at the weekend and delivered a superb showing, finding himself unlucky not to add an assist to his contributions after making one key pass and creating one big chance.
FWD - Matheus Cunha, 8.6 (Wolves)
Wolves forward Matheus Cunha helped to dampen concerns about his future at the club with a goal in his side's 4-2 win over Spurs.
The forward didn't start the match but made the most of his 20 minutes on the pitch by wrapping up the three points for his side late in the game after racing through and slotting a cool finish into the bottom corner.
FWD - Joao Pedro, 8.8 (Brighton)
Another Brazilian to play a starring role over the weekend was Brighton forward Joao Pedro, who netted twice in their 2-2 draw with Leicester.
Pedro bagged two penalties to put an end to the Seagulls' three-match losing run and earned an 8.8 player rating in the process - the joint-highest of anyone across the latest round of fixtures.
FWD - Jadon Sancho, 8.1 (Chelsea)
Jadon Sancho has endured a difficult season since joining Chelsea on loan from Manchester United, but he proved his worth by scoring a late equaliser in their draw with Ipswich.
The winger was brought onto the pitch late in the match to rescue something for the Blues and did just that, curling an outrageous effort into the top corner with just 10 minutes left to play.