PSV already played one official game before Saturday's league season opener - the Eindhoven side beat Go Ahead Eagles 2-1 on Sunday to win the Johan Cruyff Shield.
As opposed to last Sunday, Ruben van Bommel was handed his first official start for PSV after the former AZ winger recovered from a back injury. Alassane Plea was given his second-straight start, too, with striker Ricardo Pepi still not fit enough to play.
Visitors Sparta saw four new players start, including former PSV goalkeeper Joel Drommel. Jens Toornstra and FC Twente loanee Sayf Ltaief formed the attacking midfield, and former Dutch international Bruno Martins Indi wore the captain's armband in his first game for Sparta.
The game started disastrously for Sparta, who conceded their first goal of the season within two minutes when Joel Drommel left his near corner wide open and let Ruben van Bommel surprise him with a shot with the outside of his foot.
As Sparta tried to make life for PSV difficult, Ivan Perisic doubled the lead for the home side in the 40th minute from a corner. Right-back Sergino Dest officially put the game out of reach for Sparta in added time with a thunderous effort.
As good as Sparta's intentions were coming out of half-time, as lousy was their defending when Joey Veerman was left to shoot freely at Joel Drommel, who made another mistake as he let Veerman's shot slip through his hands.
Sayf Ltaief celebrates his Sparta debut with a goal after Shunsuke Mito escaped from PSV's back line and laid the ball of to a wide-open Ltaief, who got one back for Sparta after an hour.
Guus Til put PSV up 5-1 after being left wide open by Sparta's defence, after which Spanish centre-half Yarek Gasiorowski put the final score of 6-1 on the board with a header from a corner.
PSV opened their season with an emphatic win and now get to look forward to next week's challenge - an away game at FC Twente.
View all the match statistics on Flashscore.
