Hollands was seen acting erratically and at times appearing disoriented during a performance in which he registered just one kick despite spending 84% of the first three quarters of the match on the field.
Carlton described it as a "mental health episode" after the match to quell speculation of the cause of Hollands' behaviour and the 47-gamer, who turns 24 on Saturday, was admitted to hospital on Monday night for undisclosed reasons.
Hollands volunteered to undergo drug testing post-game, whilst on Friday club CEO Graham Wright expressed a firm belief that Hollands was not under the influence of any drugs or alcohol on the night.
It has seen been revealed that Hollands, who has battled with mental health issues throughout his brief career, expressed to the club on Thursday afternoon some fresh struggles before convincing club medical officials that he would be able to play against Collingwood.
Hollands' behaviour during and prior to the match was widely reported on social media, whilst it is believed that his Carlton teammates actively avoided passing the ball to him during the game because of his uncharacteristic conduct.
The club has since launched an internal investigation into the matter, which the AFL will be quickly but comprehensively responding to.
Whilst not yet launching an official investigation of their own and not receiving any such complaints, WorkSafe Victoria has confirmed they will be "assessing the matter to determine whether any action is required", according to NewsWire.
Reports of Hollands expressing his mental health struggles prior to the bring will question Carlton's overall handling of his off-field struggles throughout the year.
Any official WorkSafe investigation would likely look into club policies and protocols and whether approving Hollands to play last Thursday night was a breach of the Occupational Health and Safety Act, but the statutory body may await the results of investigations from the club and the AFL beforehand.