The 36-year-old played 206 games with the Eagles, the most in franchise history, with a record of 76.5 sacks (third in franchise history), 487 total tackles, 126 for a loss, 153 QB hits and 22 forced fumbles.
In an emotional press conference, Graham spoke to the fanbase, explaining: "Through the struggles, the injuries and moments, I had to prove myself again. You never let me get comfortable. You held me accountable. You kept that chip on my shoulder.
"You pushed me to be better and when the time came, we celebrated together, two times. This city is built off hard work, resilience and unmatched passion. You bring the same energy to every game, every moment and every season. Your loyalty, your fire and unwavering support mean everything to me and this organisation."
"Brandon Graham is the embodiment of everything you want in a Philadelphia Eagle," team owner Jeffrey Lurie said in a statement.
".. It was the way he played the game and the way he carried himself that earned him the love and respect of his coaches, teammates and fans."
His last game with the Eagles was Super Bowl LVIII, which saw him win his second championship as they beat the Kansas City Chiefs 40-22. The DE made one tackle during the game and goes out as one the team's all-time greats.