Having only one season as a manager in senior football under his belt and being fairly flexible (more on that later), Van Nistelrooy doesn't have the strongest tactical identity, but there are some principles in and out of possession that he's generally stuck by.
So, let's take a look at how he's likely to set up his Leicester side.
Box midfield
Like Pep Guardiola, Mikel Arteta and numerous other managers, Van Nistelrooy likes his teams to play with a box midfield in possession, a setup with two defensive midfielders sitting behind two number 10s.
This can be achieved by a defender stepping into midfield when his side have the ball - as is the case at Manchester City and Arsenal - or by a winger tucking inside and full-back moving forward into his position, and it's the latter setup that Van Nistelrooy usually went with at PSV.
The side would play a 4-2-3-1 off the ball but left-winger Cody Gakpo would become a second number 10 in possession before he left the club in the winter after which Xavi Simons was given that role. On the right, Noni Madueke or Johan Bakayoko would hug the touchline with the full-back staying back to form a back three.
The fact that Gakpo and Xavi ended the season as the two players with the most goal contributions while Bakayoko got 10 in 17 league starts shows just how important wingers are in Van Nistelrooy's side with most of the attacks going through the flanks.
All in all, his attacking approach was largely successful with the team scoring the most goals in the Eredivisie that season, although he was somewhat reliant on the talent and initiative of his forwards and often struggled to find ways to break down organised low blocks himself.
Mid-block
Van Nistelrooy took over a PSV side that held a high backline and began pressing well inside the opposition half under previous manager Roger Schmidt, but the Dutchman preferred a more conservative approach.
His side wouldn't sit particularly deep off the ball but wouldn't push high up the field either, sitting in a compact narrow block and not pressing until the opposition moved the ball forward to a full-back or centre-midfielder, with not a huge amount of pressure being put on their goalkeeper and centre-backs.
This caused problems for the coach at first with his forwards often still pressing high as they had under Schmidt but his backline sitting fairly deep as instructed by him, leaving huge gaps in the side's defensive structure. Largely because of this, they kept just five clean sheets under their new manager in the first half of the season.
Things did improve defensively once they'd become more familiar with the setup with that number rising to nine in the second half of the campaign. However, Van Nistelrooy's PSV were defensively fragile more often than not and conceded more goals than five other Eredivisie teams in his sole campaign, including three with considerably weaker squads.
He'll struggle to succeed with a side likely to be without the ball more often than not if he hasn't improved his defensive tactics since leaving PSV, but there were some signs in his four-match interim spell at Manchester United that he's done so with the club keeping two clean sheets and giving away only 1.10 xG in a 1-1 draw against a strong Chelsea side.
Adaptability
Perhaps the biggest compliment that can be paid to Van Nistelrooy so far in his managerial career is his ability to adapt to different opponents and situations.
A good example of this ability is the fact that while over the course of the season, his side had an average of 55.5% possession, that average dropped to 39.3% for the six matches played against the Netherlands' two other biggest clubs - Ajax and Feyenoord - and PSV won five and drew one of those matches.
In most of those games as well as a 2-0 win over Arsenal in the Europa League group stage, Van Nistelrooy would have his side sit deeper off the ball and be more direct on the ball, with them producing a number of lethal counter-attacks as a result.
His reactive tactics won him the majority of games against top sides and saw him get the better of elite managers Mikel Arteta and Arne Slot, and they also won PSV the Dutch Cup.
It was his issues when needing to be proactive against weaker sides rather than failings in big games that saw them finish second to Slot's Feyenoord in the league, but he did also show a willingness to learn from his mistakes and tweak his tactics as the season went on rather than sticking to approaches that weren't working.
How will Van Nistelrooy's Leicester play?
As already mentioned, Van Nistelrooy's biggest successes at PSV came when he played counter-attacking football, and he might play that kind of football more often than not rather than primarily adopt a more possession-based approach at Leicester.
He did so at PSV when up against evenly-matched or stronger sides, and most Premier League teams fall into that category for his new club with their squad undoubtedly one of the weaker ones in England's top flight.
In terms of the setup, Brighton loanee Facundo Buonanotte seems ideally suited to playing the role of a narrow winger on the right which could mean the right-back in the likely 4-2-3-1 system would be asked to bomb forward with the left-back staying deep and the left-winger staying wide.
Van Nistelrooy's midfield pivot at PSV usually consisted of one more physical enforcer (Ibrahim Sangare) and one creative playmaker (Joey Veerman), so he could go with Wilfred Ndidi and Harry Winks to create a similar dynamic at his new club.
